National Institute of Nutrition
Hyderabad-500 007, India.
Ph No: #+914027197200
Email: email@example.com , firstname.lastname@example.org
Dr.A.Vajreswari, M.Sc., Ph.D
Dr.A.Vajreswari, presently serving as Scientist F and Head, Lipid Biochemistry Division of the institute. She earned her post graduate degree (M.Sc.) from Andhra University, Visakhapatnam and Doctoral degree (Ph.D.) from Osmania University in Biochemistry, Hyderabad. She is a member of various scientific bodies; Indian Women Scientist Association and American Oil Chemist Society & its various divisions. She served as reviewer for Food Agricultural Research Council, England and Biotech & Biotechnological Science Research Council, England. She is a recognized research supervisor in biochemistry, Osmania University and several research students are working for doctoral studies. She has several well cited and high impact publications to her credit.
Her broad area of research is on dietary fats/oils and their impact on human health and diseases particularly dyslipidemia, obesity and insulin resistance. Also, current focus is on how various classes of fatty acids and vitamin A affect the development of obesity and insulin resistance using both genetic and diet-induced obese rat models.
List of Publications:
Vajreswari A, Rao PS, Kaplay SS, Tulpule PG. Erythrocyte membrane in rats fed high erucic acid-containing mustard oil: osmotic fragility, lipid composition, and (Na+, K+)- and (Ca2+, Mg2+)-ATPases. Biochem Med. 1983 ; 29:74-84
Vajreswari A, Narayanareddy K, Rao PS. Fatty acid composition of erythrocyte membrane lipid obtained from children suffering from kwashiorkor and marasmus. Metabolism. 1990;39:779-82.
Vajreswari A, Narayanareddy K. Effect of dietary fats on erythrocyte membrane lipid composition and membrane-bound enzyme activities. Metabolism. 1992; 41: 352-8.
Vajreswari A, Narayanareddy K. Effect of dietary fats on some membrane-bound enzyme activities, membrane lipid composition and fatty acid profiles of rat heart sarcolemma. Lipids. 1992; 27: 339-43
Srinivasarao P, Narayanareddy K, Vajreswari A, Rupalatha M, Prakash PS, Rao P. Influence of dietary fat on the activities of subcellular membrane-bound enzymes from different regions of rat brain. Neurochem Int. 1997; 31: 789-94.
Vajreswari A, Rupalatha M, Rao PS. Effect of altered dietary n-6-to-n-3 fatty acid ratio on erythrocyte lipid composition and membrane-bound enzymes. J Nutr Sci Vitaminol (Tokyo). 2002; 48: 365-70.
Jeyakumar SM, Vajreswari A, Giridharan NV Vitamin A supplementation induces adipose tissue loss through apoptosis in lean but not in obese rats of the WNIN/Ob strain. J Mol Endocrinol. 2005; 35: 391-398.
Jeyakumar SM, Vajreswari A, Giridharan NV. Chronic dietary vitamin A supplementation regulates obesity in an obese mutant WNIN/Ob rat model. Obesity (Silver Spring). 2006; 14: 52-59.
Jeyakumar SM, Vajreswari A, Giridharan NV. Impact of vitamin A on high-density lipoprotein-cholesterol and scavenger receptor class BI in the obese rat. Obesity (Silver Spring). 2007; 15: 322-329.
Vajreswari A and Jeyakumar SM. Retinoids: Impact on adiposity, lipids and lipoprotein metabolism. Review. Recent patents on Endocrine, Metabolic and Immune drug discovery. 2008; 2: 109-122.
Jeyakumar SM, Vajreswari A, Giridharan NV. Vitamin A regulates obesity in WNIN/Ob obese rat; independent of stearoyl-CoA desaturase-1. Biochem Biophys Res Commun. 2008; 370: 243-247.
Sheril A, Jeyakumar SM, Jayashree T, Giridharan NV, Vajreswari A. Impact of feeding polyunsaturated fatty acids on cholesterol metabolism of dyslipidemic obese rats of WNIN/GR-Ob strain. Atherosclerosis. 2009; 204: 136-140.
Jeyakumar SM, Lopamudra P, Padmini S, Balakrishna N, Giridharan NV, Vajreswari A. Fatty acid desaturation index correlates with body mass and adiposity indices of obesity in Wistar NIN obese mutant rat strains WNIN/Ob and WNIN/GR-Ob. Nutr Metab (Lond). 2009; 6: 27.
Vara Prasad SS, Jeya Kumar SS, Kumar PU, Qadri SS, Vajreswari A. Dietary fatty acid composition alters 11β-hydroxysteroid dehydrogenase type 1 gene expression in rat retroperitoneal white adipose tissue. Lipids Health Dis. 2010; 9: 111.
Prasad SS, Prashanth A, Kumar CP, Reddy SJ, Giridharan NV, Vajreswari A. A novel genetically-obese rat model with elevated 11 beta-hydroxysteroid dehydrogenase type 1 activity in subcutaneous adipose tissue. Lipids Health Dis. 2010; 9: 132.
Kalpagam Polasa. Toxicological evaluation of certain veterinary drug residues in food. J. Food Science Technology. 32(3): 259, 1995
Kalpagam Polasa. The environmental health criteria. 159. Glyphosate (WHO) J. Food Science Technology. 32 (6) 522, 1995
Kalpagam Polasa. Evaluation of certain veterinary drug residues in food, IJMR. 16(2), 166-167, 2007
Kalpagam Polasa. Evaluation of Certain Food Additives and Contaminants, IJMR. 129; January 2009, 112-114.
“Lipids” Ghafoorunissa and A. Vajreswari. In: Text book of Human Nutrition (Mahtab S. Bamji, N. Pralhad Rao and Vinodini Reddy eds.) pp 47-63, published by Oxford IBH publishing Co. Ltd. New Delhi.(updated in 2009).